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Target
Tyrosine-protein kinase transforming protein Src [144-247,E177Q,S178L,E179A,T180R,T181V,C186A,K201L]
Ligand
BDBM195583
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Assay
pH
7.3500±n/a
Kd
7.7±0.6 nM
Comments
extracted
Citation
 Ju, T; Niu, W; Guo, J Evolution of Src Homology 2 (SH2) Domain to Recognize Sulfotyrosine. ACS Chem Biol 11:2551-7 (2016) [PubMed]  Article 
Target
Name:
Tyrosine-protein kinase transforming protein Src [144-247,E177Q,S178L,E179A,T180R,T181V,C186A,K201L]
Synonyms:
Src homology 2 domain mutant (E36Q/S37L/E38A/T39R/T40V/C45A/K60L) | SRC_RSVSE | V-SRC | Src homology 2 domain mutant (SH2-58.6)
Type:
Protein
Mol. Mass.:
11932.98
Organism:
RSV-SR-B
Description:
P63185[144-247,E177Q,S178L,E179A,T180R,T181V,C186A,K201L]
Residue:
104
Sequence:
QAEEWYFGKITRRESERLLLNPENPRGTFLVRQLARVKGAYALSVSDFDNAKGLNVLHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTNVCPT
  
Inhibitor
Name:
BDBM195583
Synonyms:
Phosphotyrosine (pTyr)
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
[NH3+][C@@H](Cc1ccc(OP([O-])([O-])=O)cc1)C([O-])=O |r|
Structure:
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