Reaction Details Report a problem with these data
Target
Macrophage colony-stimulating factor 1 receptor [555-568]
Ligand
BDBM198873
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Competition Immunoassay
pH
7.5±n/a
IC50
0.6±n/a nM
Comments
extracted
Citation
 Illig, CR; Ballentine, SK; Chen, J; Desjarlais, RL; Meegalla, SK; Wall, M; Wilson, K Inhibitors of c-fms kinase US Patent  US9221797 Publication Date 12/29/2015 
Target
Name:
Macrophage colony-stimulating factor 1 receptor [555-568]
Synonyms:
CSF1R | CSF1R_HUMAN | FMS | FMS (aa 555-568) peptide | FMS Substrate Peptide (aa 555-568) | Macrophage colony-stimulating factor 1 receptor (CSF1R) or (c-fms)
Type:
Peptide
Mol. Mass.:
1619.64
Organism:
Homo sapiens (Human)
Description:
P07333 aa 555-568
Residue:
14
Sequence:
SYEGNSYTFIDPTQ
  
Inhibitor
Name:
BDBM198873
Synonyms:
US9221797, 45
Type:
Small organic molecule
Emp. Form.:
C26H33N5O
Mol. Mass.:
431.5731
SMILES:
CC1CCCC(=C1C)c1cc(ccc1NC(=O)c1ncc([nH]1)C#N)C(C)(C)N1CCCC1 |c:5|
Structure:
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