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Target
Coproheme decarboxylase
Ligand
BDBM209868
Substrate
n/a
Meas. Tech.
UV-Visible Titration Assay
pH
6.8±n/a
Temperature
298.15±n/a K
Kd
720±0.21 nM
Comments
extracted
Citation
 Mayfield, JA; Hammer, ND; Kurker, RC; Chen, TK; Ojha, S; Skaar, EP; DuBois, JL The chlorite dismutase (HemQ) from Staphylococcus aureus has a redox-sensitive heme and is associated with the small colony variant phenotype. J Biol Chem 288:23488-504 (2013) [PubMed]  Article 
Target
Name:
Coproheme decarboxylase
Synonyms:
CHDC_STAAB | Chlorite dismutase (HemQ) | chdC
Type:
Protein
Mol. Mass.:
29320.74
Organism:
Staphylococcus aureus
Description:
Q2YS77
Residue:
250
Sequence:
MSQAAETLDGWYSLHLFYAVDWASLRLAPKDERDALVTELQSFLENTATVRSSKSGDQAIYNITGQKADLLLWFLRPEMKSLNHIENEFNKLRIADFLIPTYSYVSVIELSNYLAGKSDEDPYENPHIKARLYPELPHSDYICFYPMNKRRNETYNWYMLTMEERQKLMYDHGMIGRKYAGKIKQFITGSVGFDDFEWGVTLFSDDVLQFKKIVYEMRFDETTARYGEFGSFFVGHIINTNEFDQFFAIS
  
Inhibitor
Name:
BDBM209868
Synonyms:
3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid;iron(2+) | Haemin | Heme
Type:
Small organic molecule
Emp. Form.:
C34H32N4O4
Mol. Mass.:
560.6434
SMILES:
Cc1c(C=C)c2cc3[n-]c(cc4[n-]c(cc5nc(cc1n2)c(C=C)c5C)c(C)c4CCC(O)=O)c(CCC(O)=O)c3C
Structure:
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