Reaction Details Report a problem with these data
Target
N-acetyltransferase domain-containing protein
Ligand
BDBM213238
Substrate
n/a
Meas. Tech.
Isothermal Titration Calorimetry (ITC)
pH
7.5±0
Temperature
298.15±0 K
Kd
3.8e+3± 5e+2 nM
Citation
 Majorek, KA; Kuhn, ML; Chruszcz, M; Anderson, WF; Minor, W Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa. J Biol Chem 288:30223-35 (2013) [PubMed]  Article 
Target
Name:
N-acetyltransferase domain-containing protein
Synonyms:
Gcn5-related N-acetyltransferases (GNAT) superfamily protein PA4794 (PA4794)
Type:
Protein
Mol. Mass.:
17787.24
Organism:
Pseudomonas aeruginosa
Description:
Q9HV14
Residue:
160
Sequence:
MQLSHRPAETGDLETVAGFPQDRDELFYCYPKAIWPFSVAQLAAAIAERRGSTVAVHDGQVLGFANFYQWQHGDFCALGNMMVAPAARGLGVARYLIGVMENLAREQYKARLMKISCFNANAAGLLLYTQLGYQPRAIAERHDPDGRRVALIQMDKPLEP
  
Inhibitor
Name:
BDBM213238
Synonyms:
AcCoA
Type:
Small organic molecule
Emp. Form.:
C23H38N7O17P3S
Mol. Mass.:
809.571
SMILES:
CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12
Structure:
Search PDB for entries with ligand similarity: