Reaction Details Report a problem with these data
Target
Serine/threonine-protein kinase pim-2
Ligand
BDBM225047
Substrate
n/a
Meas. Tech.
Enzyme Assay
IC50
717.262±n/a nM
Citation
 Wang, H; Cee, VJ; Herberich, BJ; Jackson, CL; Lanman, BA; Nixey, T; Pettus, LH; Reed, AB; Wu, B; Wurz, R; Tasker, A Azole compounds as PIM inhibitors US Patent  US9321756 Publication Date 4/26/2016 
Target
Name:
Serine/threonine-protein kinase pim-2
Synonyms:
PIM2 | PIM2_HUMAN | Pim-2h | Serine/threonine-protein kinase (PIM2) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase pim-2 (PIM2)
Type:
Serine/threonine-protein kinase
Mol. Mass.:
34185.93
Organism:
Human
Description:
Q9P1W9
Residue:
311
Sequence:
MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKGGPAPLAWSLLP
  
Inhibitor
Name:
BDBM225047
Synonyms:
US9321756, 9
Type:
Small organic molecule
Emp. Form.:
C15H10FN5O
Mol. Mass.:
295.2712
SMILES:
Nc1nnc(o1)-c1ccc2[nH]cc(-c3ccccc3F)c2n1
Structure:
Search PDB for entries with ligand similarity: