Reaction Details Report a problem with these data
Target
Pancreatic triacylglycerol lipase
Ligand
BDBM224807
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
6.8±n/a
IC50
3.12e+4± 1.3e+3 nM
Comments
extracted
Citation
 Chung, BY; Kim, TH; Lee, SS; Bai, H; Lee, S; Park, CH Rotenone derivatives and a use thereof US Patent  US9328123 Publication Date 5/3/2016 
Target
Name:
Pancreatic triacylglycerol lipase
Synonyms:
LIPP_PIG | PL | PNLIP | PTL | Pancreatic lipase | Pancreatic triacylglycerol lipase
Type:
Enzyme
Mol. Mass.:
50080.69
Organism:
Sus scrofa (Pig)
Description:
P00591
Residue:
450
Sequence:
SEVCFPRLGCFSDDAPWAGIVQRPLKILPWSPKDVDTRFLLYTNQNQNNYQELVADPSTITNSNFRMDRKTRFIIHGFIDKGEEDWLSNICKNLFKVESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEVLKSSLGYSPSNVHVIGHSLGSHAAGEAGRRTNGTIERITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDAAPIIPNLGFGMSQTVGHLDFFPNGGKQMPGCQKNILSQIVDIDGIWEGTRDFVACNHLRSYKYYADSILNPDGFAGFPCDSYNVFTANKCFPCPSEGCPQMGHYADRFPGKTNGVSQVFYLNTGDASNFARWRYKVSVTLSGKKVTGHILVSLFGNEGNSRQYEIYKGTLQPDNTHSDEFDSDVEVGDLQKVKFIWYNNNVINPTLPRVGASKITVERNDGKVYDFCSQETVREEVLLTLNPC
  
Inhibitor
Name:
BDBM224807
Synonyms:
Gamma-irradiated rotenone | US9328123, Rotenone B
Type:
Small organic molecule
Emp. Form.:
C27H28O9
Mol. Mass.:
496.5058
SMILES:
COc1cc2OC[C@H]3Oc4c5C[C@@H](Oc5ccc4[C@@]4(CC5O[C@]5(O)[C@@H](O)O4)[C@H]3c2cc1OC)C(C)=C |r|
Structure:
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