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Target
Heme-binding protein A
Ligand
BDBM225231
Substrate
n/a
Meas. Tech.
Isothermal Titration Calorimetry (ITC)
pH
7.4±0
Temperature
310.15±0 K
Kd
3.3e+2± 5e+1 nM
Citation
 Vergauwen, B; Van der Meeren, R; Dansercoer, A; Savvides, SN Delineation of the Pasteurellaceae-specific GbpA-family of glutathione-binding proteins. BMC Biochem 12:59 (2011) [PubMed]  Article 
Target
Name:
Heme-binding protein A
Synonyms:
Glutathione-binding protein (GbpAAp) | Heme-binding protein A
Type:
Protein
Mol. Mass.:
60509.59
Organism:
Actinobacillus pleuropneumoniae
Description:
ZP_07529013.1
Residue:
545
Sequence:
MKLANLTKVSAAVLAVLALAACDDKNADGKTTAKPAAEKTFVNCVSRSPQYFSPALAMDGISYNASSQQVYNRLVEFKRGSTEIEPALAESWDISEDGLTYTFHLRKGVKFHSNKEFTPSRDFNADDVVFSFNRQLDPNHPYHTVSKATYPYFKAMKFPTLLKSVEKVDDHTVKFTLTKRDATFVSSLGMDFTSIYSAEYADAMLKAGKPETIDTTPIGTGPFAFTGYVLDQASRYVAYKDYWKGKADFDRLIFEIVPDATARYAKLQAGQCDLIDFPNATDIEKMKTDPKVQLLSQPGLNIAYVAFNTEKAPFDNVKVRQALNLAVDKKAIIDVVYQGAGIAAKNPLPPTIWGYNDSLAESEFNIEKAKQLLAEAGYPNGFETELWVQPVVRASNPNPRRMSEIIQADWAKIGVKAKLVTYEWGDYIKRTKAGELTAGTYGWSGDNGDPDNFLSPLFGSANVGNSNYARFNSPELDALLDKALGLSDKAERTKLYEQAQALLREQAPWINVAHSINFAPTSKRVQDYKQSPFGYTYLYGTKLAD
  
Inhibitor
Name:
BDBM225231
Synonyms:
Disulfide, Glutathione | GSSG | OXIGLUTATIONE | Oxidized Glutathione
Type:
Small organic molecule
Emp. Form.:
C20H32N6O12S2
Mol. Mass.:
612.631
SMILES:
N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O
Structure:
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