Reaction Details Report a problem with these data
Target
Urokinase-type plasminogen activator [179-424,C299A,N323Q]
Ligand
BDBM92320
Substrate
n/a
Meas. Tech.
Photometric_Method1
Ki
94±n/a nM
Citation
 D3R, DD Abbott Urokinase D3R 227:0 (2015) [PubMed] 
Target
Name:
Urokinase-type plasminogen activator [179-424,C299A,N323Q]
Synonyms:
PLAU | UROK_HUMAN | Urokinase
Type:
n/a
Mol. Mass.:
27687.84
Organism:
Homo sapiens (Human)
Description:
P00749[179-424,C299A,N323Q]
Residue:
246
Sequence:
IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTIALPSMYNDPQFGTSCEITGFGKEQSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTK
  
Inhibitor
Name:
BDBM92320
Synonyms:
uPa_42
Type:
n/a
Emp. Form.:
C28H33N3O
Mol. Mass.:
427.5811
SMILES:
COc1cc(cc2ccc(cc12)C(N)=N)C1CC1c1ccc2CCN(C)C(C(C)C)c2c1
Structure:
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