Reaction Details
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Fatty acid-binding protein 5 [K24A,R33A,K34A]
Ligand
BDBM60927
Substrate
n/a
Meas. Tech.
Ligand Binding Assay
pH
8.2±n/a
Temperature
303.15±n/a K
Kd
1.264e+4±n/a nM
Comments
extracted
Citation
Armstrong, EH; Goswami, D; Griffin, PR; Noy, N; Ortlund, EA Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor ß/d (FABP5-PPARß/d) signaling pathway. J Biol Chem 289:14941-54 (2014) [PubMed] Article More Info.:
Target
Name:
Fatty acid-binding protein 5 [K24A,R33A,K34A]
Synonyms:
FABP5 | FABP5_HUMAN | Fatty acid-binding protein 5 (FABP5)(NLSm)
Type:
Protein
Mol. Mass.:
14962.47
Organism:
Homo sapiens (Human)
Description:
Human FABP5 NLS-deficient mutant (K24A/K34A/R33A)
Residue:
135
Sequence:
MATVQQLEGRWRLVDSKGFDEYMAELGVGIALAAMGAMAKPDCIITCDGKNLTIKTESTLKTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVECVMNNVTCTRIYEKVE
Inhibitor
Name:
BDBM60927
Synonyms:
1-anilinonaphthalene-8-sulfonic acid | 8-Anilino-1-naphthalenesulfonic acid | ANS | Anilinonaphthalene-8-sulfonic acid (ANS) | BDBM50126831
Type:
n/a
Emp. Form.:
C16H13NO3S
Mol. Mass.:
299.344
SMILES:
OS(=O)(=O)c1cccc2cccc(Nc3ccccc3)c12
Structure:
