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Target
Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (A1-A) 68-320]
Ligand
BDBM7460
Substrate
n/a
Meas. Tech.
Surface Plasmon Resonance (SPR) Assay
pH
4±n/a
Kd
1.7e+3±n/a nM
Comments
extracted
Citation
 Ko, CC; Chen, YJ; Chen, CT; Liu, YC; Cheng, FC; Hsu, KC; Chow, LP Chemical proteomics identifies heterogeneous nuclear ribonucleoprotein (hnRNP) A1 as the molecular target of quercetin in its anti-cancer effects in PC-3 cells. J Biol Chem 289:22078-89 (2014) [PubMed]  Article 
Target
Name:
Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (A1-A) 68-320]
Synonyms:
HNRNPA1 | HNRPA1 | Heterogeneous nuclear ribonucleoprotein A1 (A1-A) [268-320] | Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1)(aa 268-320) | ROA1_HUMAN
Type:
Protein
Mol. Mass.:
5351.63
Organism:
Homo sapiens (Human)
Description:
Human hnRNPA1 C-terminal region (268-320 aa)
Residue:
53
Sequence:
NQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF
  
Inhibitor
Name:
BDBM7460
Synonyms:
2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;hydrate | CHEMBL50 | Quercetin | Quercetin (10) | Quercetin (21) | Quercetin (Qur) | US11021454, Compound Quercetin | US9180183, Quercetin | med.21724, Compound 4
Type:
Small organic molecule
Emp. Form.:
C15H10O7
Mol. Mass.:
302.2357
SMILES:
Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O
Structure:
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