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Target
Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (A1-A) 68-320]
Ligand
BDBM7460
Substrate
n/a
Meas. Tech.
Surface Plasmon Resonance (SPR) Assay
pH
4.0000±n/a
Kd
1.7e+3±n/a nM
Comments
extracted
Citation
 Ko, CC; Chen, YJ; Chen, CT; Liu, YC; Cheng, FC; Hsu, KC; Chow, LP Chemical proteomics identifies heterogeneous nuclear ribonucleoprotein (hnRNP) A1 as the molecular target of quercetin in its anti-cancer effects in PC-3 cells. J Biol Chem 289:22078-89 (2014) [PubMed]  Article 
Target
Name:
Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (A1-A) 68-320]
Synonyms:
Heterogeneous nuclear ribonucleoprotein A1 (A1-A) [268-320] | ROA1_HUMAN | HNRNPA1 | HNRPA1 | Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1)(aa 268-320)
Type:
Protein
Mol. Mass.:
5351.63
Organism:
Human
Description:
Human hnRNPA1 C-terminal region (268-320 aa)
Residue:
53
Sequence:
NQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF
  
Inhibitor
Name:
BDBM7460
Synonyms:
2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;hydrate | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one | CHEMBL50 | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one | Quercetin | Quercetin (21) | Quercetin (Qur) | US9180183, Quercetin | Quercetin (10) | med.21724, Compound 4 | US11021454, Compound Quercetin
Type:
Small organic molecule
Emp. Form.:
C15H10O7
Mol. Mass.:
302.04
SMILES:
c1cc(c(cc1C2=C(C(=O)c3c(cc(cc3O2)O)O)O)O)O
Structure:
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