Reaction Details Report a problem with these data
Target
Neuraminidase
Ligand
BDBM234413
Substrate
n/a
Meas. Tech.
NA Inhibition Assay
IC50
358000±n/a nM
Citation
 Liu, Y; Zhang, L; Gong, J; Fang, H; Liu, A; Du, G; Xu, W Design, synthesis, and biological activity of thiazole derivatives as novel influenza neuraminidase inhibitors. J Enzyme Inhib Med Chem 26:506-13 (2011) [PubMed]  Article 
Target
Name:
Neuraminidase
Synonyms:
NA | NRAM_I82A7 | Neuraminidase (NA)
Type:
Enzyme
Mol. Mass.:
49917.65
Organism:
Influenza A virus H3N2
Description:
Q67344
Residue:
446
Sequence:
MQIAILVTTVTLHFNQYECDSLADNQVMPCEPIIIERNITEIIYLTNTTIEKEICPKLMEYRNWSRPQCKITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNDTIHDRIPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCVTGDDKNATASFIYDGRLVDSMGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTRILFIEEGKIVHISPLSGSAQHVEECSCYPRYPSVRCICRDNWKGSNRPIVDINIKDYSIDSRYVCSGLVGDTPRNNDRSSSSDCKNPNNDKGNHGVKGWAFDDGNDVWMGRTISKDSRSGYETFKVIDGWSTPNSKSQINRQVIVDRDNRSGYSGIFSVESKGCINRCFYVELIRGRKQETRVWWTSSSIVVFCGTSGTYGKGSWPDGANINFMPI
  
Inhibitor
Name:
BDBM234413
Synonyms:
NA inhibitor, 1
Type:
Small organic molecule
Emp. Form.:
C6H8N2OS
Mol. Mass.:
156.206
SMILES:
CC(=O)Nc1nc(C)cs1
Structure:
Search PDB for entries with ligand similarity: