Reaction Details Report a problem with these data
Target
Glutathione peroxidase 1
Ligand
BDBM50422689
Substrate
n/a
Meas. Tech.
Glutathione Peroxidase Activity Assay
pH
7±n/a
Ki
32700±n/a nM
IC50
44300±n/a nM
Comments
extracted
Citation
 Ekinci, D; Cankaya, M; Gül, Ä°; Coban, TA Susceptibility of cord blood antioxidant enzymes glutathione reductase, glutathione peroxidase and glutathione S-transferase to different antibiotics: in vitro approach. J Enzyme Inhib Med Chem 28:824-9 (2013) [PubMed]  Article 
Target
Name:
Glutathione peroxidase 1
Synonyms:
Cellular glutathione peroxidase | GPX1 | GPX1_HUMAN | GPx-1 | GSHPx-1 | Glutathione peroxidase 1 (GPx)
Type:
Enzyme
Mol. Mass.:
21937.89
Organism:
Homo sapiens (Human)
Description:
P07203
Residue:
202
Sequence:
MCAARLAAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAGAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA
  
Inhibitor
Name:
BDBM50422689
Synonyms:
640/359 | CEFUROXIME
Type:
Small organic molecule
Emp. Form.:
C16H16N4O8S
Mol. Mass.:
424.385
SMILES:
CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16|
Structure:
Search PDB for entries with ligand similarity: