Reaction Details Report a problem with these data
Target
Parathyroid hormone [32-65]
Ligand
BDBM64565
Substrate
n/a
Meas. Tech.
cAMP Assay
pH
7.4±n/a
EC50
12000±n/a nM
Comments
extracted
Citation
 Nishimura, Y; Esaki, T; Tamura, T Hydantoin derivative US Patent  US9428505 Publication Date 8/30/2016 
Target
Name:
Parathyroid hormone [32-65]
Synonyms:
PTH | PTHY_HUMAN | Parathyroid hormone (PTH)
Type:
Enzyme
Mol. Mass.:
4120.23
Organism:
Homo sapiens (Human)
Description:
Human PTH(1-34) purchased from Peptide Institute, Inc.
Residue:
34
Sequence:
SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF
  
Inhibitor
Name:
BDBM64565
Synonyms:
US9428505, Compound 9
Type:
n/a
Emp. Form.:
C32H37F3N6O6S
Mol. Mass.:
690.733
SMILES:
CN1CCC2(CC1)N(C(=O)NC2=O)c1cc(C)c(CCS(=O)(=O)N2CCC3(CC2)N=C(NC3=O)c2ccc(OC(F)(F)F)cc2)c(C)c1 |c:32|
Structure:
Search PDB for entries with ligand similarity: