Reaction Details Report a problem with these data
Target
Prostaglandin F2-alpha receptor
Ligand
BDBM244799
Substrate
n/a
Meas. Tech.
Inhibition Assay
Ki
1±0.0 nM
Citation
 Page, PN; Schwarz, M; Jorand-Lebrun, C; Quattropani, A; Pomel, V α-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof US Patent  US9447055 Publication Date 9/20/2016 
Target
Name:
Prostaglandin F2-alpha receptor
Synonyms:
PF2R_HUMAN | PGF receptor | PGF2 alpha receptor | PGF2-alpha receptor | PTGFR | Prostaglandin F | Prostanoid FP receptor
Type:
Enzyme
Mol. Mass.:
40072.29
Organism:
Homo sapiens (Human)
Description:
P43088
Residue:
359
Sequence:
MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
  
Inhibitor
Name:
BDBM244799
Synonyms:
US9447055, I
Type:
Small organic molecule
Emp. Form.:
C30H34FN3O5S2
Mol. Mass.:
599.736
SMILES:
CC(C)[C@H](N)C(=O)OCC[C@H](NC(=O)[C@@H]1SCCN1S(=O)(=O)c1ccc(cc1)-c1ccccc1)c1ccc(F)cc1 |r|
Structure:
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