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Target
Bromodomain-containing protein 4 [368-440]
Ligand
BDBM259884
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
1.872±n/a nM
Citation
 Durden, DL; Morales, GA; Garlich, JR Thienopyranones as kinase and epigenetic inhibitors US Patent  US9505780 Publication Date 11/29/2016 
Target
Name:
Bromodomain-containing protein 4 [368-440]
Synonyms:
BRD4 | BRD4_HUMAN | Bromo domain 2 | Bromodomain-containing protein 4 (BD2) | Bromodomain-containing protein 4 (BRD4) Bromo 2 | Bromodomain-containing protein 4 (BRD4)(BD2) | Bromodomain-containing protein 4 (BRD4)(Bromo 2) | Bromodomain-containing protein 4 Bromo 2 domain(BRD4 BD2) | Bromodomain-containing protein 4 Bromodomain 2 (BRD4-2) | Bromodomain-containing protein 4 Domain 2 | HUNK1
Type:
Protein
Mol. Mass.:
8564.63
Organism:
Homo sapiens (Human)
Description:
BD2 (368-440 aa) of O60885
Residue:
73
Sequence:
KHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVV
  
Inhibitor
Name:
BDBM259884
Synonyms:
US10308662, Compound 125 | US9505780, 125
Type:
Small organic molecule
Emp. Form.:
C20H19NO4S2
Mol. Mass.:
401.499
SMILES:
CCOC(=O)c1ccc(cc1)-c1csc2c1oc(cc2=O)N1CCSCC1
Structure:
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