Reaction Details Report a problem with these data
Target
Interleukin-2
Ligand
BDBM412465
Substrate
n/a
Meas. Tech.
Human ELISA assay
IC50
14.0±n/a nM
Citation
 Chen, S; Bohnert, G; Jiang, J; Xia, Z Compounds for inflammation and immune-related uses US Patent  US10399967 Publication Date 9/3/2019 
Target
Name:
Interleukin-2
Synonyms:
IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF
Type:
Enzyme
Mol. Mass.:
17630.05
Organism:
Homo sapiens (Human)
Description:
P60568
Residue:
153
Sequence:
MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
  
Inhibitor
Name:
BDBM412465
Synonyms:
(Z)-N-(5-(1-(4-bromophenyl)prop-1- en-1-yl)pyridin-2-yl)-5-fluoro-4- methylnicotinamide hydrochloride | US10399967, Compound 136 | US10399967, Compound 96
Type:
Small organic molecule
Emp. Form.:
C21H17BrFN3O
Mol. Mass.:
426.282
SMILES:
C\C=C(\c1ccc(Br)cc1)c1ccc(NC(=O)c2cncc(F)c2C)nc1
Structure:
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