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Target
Mu-type opioid receptor
Ligand
BDBM414828
Substrate
n/a
Meas. Tech.
mu-Opioid Receptor Binding Assay
Ki
0.800±0.10 nM
Citation
 Kassick, A; Tadesse, D; Tafesse, L 6,7-cyclicmorphinan derivatives and use thereof US Patent  US10435406 Publication Date 10/8/2019 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM414828
Synonyms:
(6R,6aS,7aS,10aS,11aR)-14- (cyclopropylmethyl)-2,6a-dihydroxy- 5,6,6a,7,7a,8,10a,11-octahydro-6,11a- (epiminoethano)naphtho[2,1-f]indol- 9(10H)-one | US10435406, Compound 10
Type:
Small organic molecule
Emp. Form.:
C22H28N2O3
Mol. Mass.:
368.4693
SMILES:
Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(C[C@@H]5NC(=O)C[C@@H]5C[C@@]34O)c2c1 |r|
Structure:
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