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Target
Cannabinoid receptor 2
Ligand
BDBM419269
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
9.00±n/a nM
Citation
 Gobbi, L; Grether, U; Guba, W; Kretz, J; Martin, RE; Westphal, MV [1,2,3]triazolo[4,5-d]pyrimidine derivatives US Patent  US10457684 Publication Date 10/29/2019 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM419269
Synonyms:
5-tert-Butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[[2-ethynyl-6-[3-(trifluoromethyl)diazirin-3-yl]phenyl]methyl]triazolo[4,5-d]pyrimidine | US10457684, Example 13
Type:
Small organic molecule
Emp. Form.:
C23H21F5N8
Mol. Mass.:
504.4585
SMILES:
CC(C)(C)c1nc(N2CCC(F)(F)C2)c2nnn(Cc3c(cccc3C3(N=N3)C(F)(F)F)C#C)c2n1 |c:28|
Structure:
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