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Target
Interleukin-6
Ligand
BDBM419219
Substrate
n/a
Meas. Tech.
Interleukin 6 Induction Assay
EC50
6.90±n/a nM
Citation
 He, L; Gangwar, S; Posy, SL; Poudel, YB; Sivaprakasam, P Toll-like receptor 7 (TLR7) agonists having a heterobiaryl moiety, conjugates thereof, and methods and uses therefor US Patent  US10487084 Publication Date 11/26/2019 
Target
Name:
Interleukin-6
Synonyms:
B-cell stimulatory factor 2 | BSF-2 | CDF | CTL differentiation factor | Hybridoma growth factor | IFN-beta-2 | IFNB2 | IL-6 | IL6 | IL6_HUMAN | Interferon beta-2
Type:
n/a
Mol. Mass.:
23717.96
Organism:
Homo sapiens (Human)
Description:
P05231
Residue:
212
Sequence:
MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
  
Inhibitor
Name:
BDBM419219
Synonyms:
US10457681, Compound Ia-04 | US10487084, Compound Ia-04 | US10981914, Compound Ia-04
Type:
Small organic molecule
Emp. Form.:
C25H29N7O2S
Mol. Mass.:
491.608
SMILES:
CCCCOc1nc(N)c2nc(O)n(Cc3ccc4N(C)c5ccc(CNC)cc5Sc4c3)c2n1
Structure:
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