Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM434804
Substrate
n/a
Meas. Tech.
Binding Assays
Ki
5.46±0.67 nM
Citation
 Jacobson, KA; Tosh, DK; Salvemini, D A3 adenosine receptor agonists US Patent  US10577368 Publication Date 3/3/2020 
Target
Name:
Adenosine receptor A3
Synonyms:
A3AR | AA3R_MOUSE | Adenosine A3 receptor | Adora3 | Gpcr2
Type:
PROTEIN
Mol. Mass.:
36460.91
Organism:
Mus musculus
Description:
ChEMBL_1515686
Residue:
319
Sequence:
MEADNTTETDWLNITYITMEAAIGLCAVVGNMLVIWVVKLNPTLRTTTVYFIVSLALADIAVGVLVIPLAIAVSLQVKMHFYACLFMSCVLLIFTHASIMSLLAIAVHRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKATLASSQNSSTLLCHFRSVVSLDYMVFFSFITWILVPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFDVKIPDVAMCLGILLSHANSMMNPIVYACKIKKFKETYFLILRAVRLCQTSDSLDSNMEQTTE
  
Inhibitor
Name:
BDBM434804
Synonyms:
US10577368, Compound 37
Type:
Small organic molecule
Emp. Form.:
C26H24FeN6O3
Mol. Mass.:
524.352
SMILES:
CNC(=O)[C@]12CC1[C@H]([C@H](O)C2O)n1cnc2c(NC)nc(nc12)C#Cc1ccc[c-]1[Fe++][c-]1cccc1 |r|
Structure:
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