Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM382319
Substrate
n/a
Meas. Tech.
[3H]-Spiperone Binding Assay
Ki
1.78±n/a nM
Citation
 Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L Substituted 3,6-diazabicyclo[3.2.0]heptanes US Patent  US10584135 Publication Date 3/10/2020 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM382319
Synonyms:
US10273244, Example 200 | US10584135, Example 200
Type:
Small organic molecule
Emp. Form.:
C24H28FN7OS
Mol. Mass.:
481.589
SMILES:
Cn1c(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2ccc(F)cc2)nnc1-c1ccc(nc1)C(N)=O |r|
Structure:
Search PDB for entries with ligand similarity: