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Target
Beta-1 adrenergic receptor
Ligand
BDBM50213118
Substrate
n/a
Meas. Tech.
Beta-AR binding assay
Ki
31440000±1681000 nM
Citation
 Wainer, IW; Bernier, M; Toll, LR; Jimenez, LA Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas US Patent  US10617654 Publication Date 4/14/2020 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1_MOUSE | Adrb1 | Adrb1r | Beta-1 adrenergic recepto | Beta-1 adrenergic receptor | Beta-1 adrenoceptor | Beta-1 adrenoreceptor
Type:
PROTEIN
Mol. Mass.:
50507.75
Organism:
Mus musculus
Description:
ChEMBL_105090
Residue:
466
Sequence:
MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAGMGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARALVCTVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPEPSPSPGPPRPADSLANGRSSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDDDDDAGTTPPARLLEPWTGCNGGTTTVDSDSSLDEPGRQGFSSESKV
  
Inhibitor
Name:
BDBM50213118
Synonyms:
(S,S)-(+)-5-{2-[2-(4-aminophenyl)-1-methylethylamino]-1-hydroxyethyl}-1,3-benzenediol | CHEMBL229390 | US10617654, Compound (S,S)-3 | US9492405, (S,S)-3 | US9492405, 12
Type:
Small organic molecule
Emp. Form.:
C17H21NO3
Mol. Mass.:
287.3535
SMILES:
C[C@@H](Cc1ccccc1)NC[C@@H](O)c1cc(O)cc(O)c1
Structure:
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