Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 2B
Ligand
BDBM453276
Substrate
n/a
Meas. Tech.
5-HT2B Agonist Activity Assay
EC50
>6000±n/a nM
Citation
 Jensen, KG; Kværnø, L; Jørgensen, M; Juhl, M Catecholamine prodrugs for use in the treatment of Parkinson's disease US Patent  US10729710 Publication Date 8/4/2020 
Target
Name:
5-hydroxytryptamine receptor 2B
Synonyms:
5-HT2 | 5-HT2B | 5-hydroxytryptamine receptor 2B | 5-hydroxytryptamine receptor 2B (5HT2B) | 5HT2B_MOUSE | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr2b
Type:
Enzyme
Mol. Mass.:
53610.91
Organism:
Mus musculus (Mouse)
Description:
Q02152
Residue:
479
Sequence:
MASSYKMSEQSTTSEHILQKTCDHLILTNRSGLETDSVAEEMKQTVEGQGHTVHWAALLILAVIIPTIGGNILVILAVALEKRLQYATNYFLMSLAIADLLVGLFVMPIALLTIMFEAIWPLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRATAFIKITVVWLISIGIAIPVPIKGIETDVINPHNVTCELTKDRFGSFMVFGSLAAFFAPLTIMVVTYFLTIHTLQKKAYLVKNKPPQRLTRWTVPTVFLREDSSFSSPEKVAMLDGSHRDKILPNSSDETLMRRMSSVGKRSAQTISNEQRASKALGVVFFLFLLMWCPFFITNLTLALCDSCNQTTLKTLLEIFVWIGYVSSGVNPLIYTLFNKTFREAFGRYITCNYRATKSVKALRKFSSTLCFGNSMVENSKFFTKHGIRNGINPAMYQSPMRLRSSTIQSSSIILLDTLLTENDGDKAEEQVSYI
  
Inhibitor
Name:
BDBM453276
Synonyms:
US10729710, Compound (Ia)
Type:
Small organic molecule
Emp. Form.:
C16H25NO
Mol. Mass.:
247.3758
SMILES:
CCCN1CCC[C@@H]2CC3=C(CCCC3=O)C[C@@H]12 |r,t:9|
Structure:
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