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Target
Galectin-1
Ligand
BDBM455404
Substrate
n/a
Meas. Tech.
fluorescence anisotropy assay
Kd
58.0±n/a nM
Citation
 Zetterberg, F; Nilsson, U; Leffler, H; Pedersen, A; Schambye, H; Brimert, T; Johnsson, R 1,1 ′-sulfanediyl-di-beta-D-galactopyranosides as inhibitors of galectins US Patent  US10730902 Publication Date 8/4/2020 
Target
Name:
Galectin-1
Synonyms:
14 kDa lectin | Galaptin | HPL | LEG1_HUMAN | LGALS1 | Lactose-binding lectin 1 | Lectin galactoside-binding soluble 1 | Putative MAPK-activating protein PM12
Type:
beta galactoside-binding protein
Mol. Mass.:
14713.53
Organism:
Homo sapiens (Human)
Description:
P09382
Residue:
135
Sequence:
MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD
  
Inhibitor
Name:
BDBM455404
Synonyms:
3,3′-Dideoxy-3-[4-(tetrahydropyran-4-yl)-1H-1,2,3-triazol-1-yl]-3′-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-1,1′-sulfanediyl-di-β-D-galactopyranoside | US10730902, Example 4
Type:
Small organic molecule
Emp. Form.:
C27H33F3N6O9S
Mol. Mass.:
674.646
SMILES:
OC[C@H]1OC(S[C@@H]2OC(CO)[C@H](O)[C@@H](C2O)n2cc(nn2)-c2cc(F)c(F)c(F)c2)[C@H](O)C(C1O)n1cc(nn1)C1CCOCC1 |r|
Structure:
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