Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM458397
Substrate
n/a
Meas. Tech.
Competition Radioligand Binding Assay
Ki
>1000±n/a nM
Citation
 Castro Palomino Laria, J; Camacho Gómez, J; El Maatougui, A Adenosine A3 receptor modulators US Patent  US10744125 Publication Date 8/18/2020 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM458397
Synonyms:
US10744125, Example 6
Type:
Small organic molecule
Emp. Form.:
C22H18FN5O3S
Mol. Mass.:
451.473
SMILES:
OC(=O)C1CCN(CC1)c1ccc(cn1)C(=O)Nc1nc(c(s1)C#N)-c1cccc(F)c1
Structure:
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