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Target
C-X-C chemokine receptor type 4
Ligand
BDBM459099
Substrate
n/a
Meas. Tech.
Binding Inhibition Assay
IC50
50±n/a nM
Citation
 Bourque, EM; Skerlj, R CXCR4 inhibitors and uses thereof US Patent  US10759796 Publication Date 9/1/2020 
Target
Name:
C-X-C chemokine receptor type 4
Synonyms:
CXC-R4 | CXCR-4 | CXCR4 | CXCR4_BOVIN | Fusin | LCR1 | LESTR | Leukocyte-derived seven transmembrane domain receptor | SDF-1 receptor | Stromal cell-derived factor 1 receptor
Type:
Protein
Mol. Mass.:
39947.89
Organism:
Bovine
Description:
P25930
Residue:
353
Sequence:
MEGIRIFTSDNYTEDDLGSGDYDSMKEPCFREENAHFNRIFLPTVYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVLTLPFWAVDAVANWYFGKFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQKPRKLLAEKVVYVGVWLPAVLLTIPDLIFADIKEVDERYICDRFYPSDLWLVVFQFQHIVVGLLLPGIVILSCYCIIISKLSHSKGYQKRKALKTTVILILTFFACWLPYYIGISIDSFILLEIIQQGCEFESTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
  
Inhibitor
Name:
BDBM459099
Synonyms:
US10759796, Compound I-77
Type:
Small organic molecule
Emp. Form.:
C26H34N6
Mol. Mass.:
430.5884
SMILES:
CN1[C@H](CCC[C@H]1c1ncccc1C)c1cn2c(cccc2n1)N1CCN2CCCC2C1 |r|
Structure:
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