Reaction Details Report a problem with these data
Target
Metallothionein-2
Ligand
BDBM50035179
Substrate
n/a
Meas. Tech.
Binding Assay
Ki
0.042±n/a nM
Citation
 Ruch Werneck Guimarães, C; Felype Zaneti De Azevedo, H; Mascarello, A; Watanabe Da Costa, R; Freire Torres Russo, V; Mannochio De Souza Russo, E Compounds, process for obtaining the compounds, pharmaceutical composition, use of the compounds and method for treating psychiatric disorders and/or sleep disorders US Patent  US10781182 Publication Date 9/22/2020 
Target
Name:
Metallothionein-2
Synonyms:
CES1 | MT-2 | MT-II | MT2 | MT2A | MT2_HUMAN | Metallothionein-2A | Metallothionein-II
Type:
Protein
Mol. Mass.:
6046.23
Organism:
Human
Description:
P02795
Residue:
61
Sequence:
MDPNCSCAAGDSCTCAGSCKCKECKCTSCKKSCCSCCPVGCAKCAQGCICKGASDKCSCCA
  
Inhibitor
Name:
BDBM50035179
Synonyms:
Agomelatine | CHEMBL10878 | N-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-acetamide | N-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-acetamide(Agomelatine) | S 20098 | US10781182, Compound IA2-76 | US11091445, Compound code IA2-76
Type:
Small organic molecule
Emp. Form.:
C15H17NO2
Mol. Mass.:
243.301
SMILES:
COc1ccc2cccc(CCNC(C)=O)c2c1
Structure:
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