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Target
Beta-arrestin-1
Ligand
BDBM224017
Substrate
n/a
Meas. Tech.
beta-Arrestin Assay
EC50
310±n/a nM
Citation
 Tounge, BA; Bayoumy, S; Kuo, LC; Dax, SL Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same US Patent  US10836728 Publication Date 11/17/2020 
Target
Name:
Beta-arrestin-1
Synonyms:
ARR1 | ARRB1 | ARRB1_HUMAN | Arrestin, beta 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47062.57
Organism:
Homo sapiens (Human)
Description:
gi_13177715
Residue:
418
Sequence:
MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
  
Inhibitor
Name:
BDBM224017
Synonyms:
(+)-Morphine | US10752592, Compound morphine | US10836728, Compound Morphine | US11534436, Compound morphine
Type:
Small organic molecule
Emp. Form.:
C17H19NO3
Mol. Mass.:
285.3377
SMILES:
CN1CC[C@]23[C@@H]4Oc5c2c(C[C@H]1[C@H]3C=C[C@H]4O)ccc5O |c:16|
Structure:
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