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Target
Beta-arrestin-1
Ligand
BDBM472834
Substrate
n/a
Meas. Tech.
beta-Arrestin Assay
EC50
>100000±n/a nM
Citation
 Tounge, BA; Bayoumy, S; Kuo, LC; Dax, SL Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same US Patent  US10836728 Publication Date 11/17/2020 
Target
Name:
Beta-arrestin-1
Synonyms:
ARR1 | ARRB1 | ARRB1_HUMAN | Arrestin, beta 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47062.57
Organism:
Homo sapiens (Human)
Description:
gi_13177715
Residue:
418
Sequence:
MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
  
Inhibitor
Name:
BDBM472834
Synonyms:
US10836728, Compound (17)
Type:
Small organic molecule
Emp. Form.:
C24H33N3O3
Mol. Mass.:
411.5371
SMILES:
COc1ccc(CCN2CCC(O)(C(CN(C)C)C2)c2cccc(c2)C(N)=O)cc1
Structure:
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