Reaction Details Report a problem with these data
Target
ADP-ribosylation factor 6
Ligand
BDBM50027961
Substrate
n/a
Meas. Tech.
Biochemical Assay1
IC50
6.70±n/a nM
Citation
 Ostanin, K; Shenderovich, M; Bajji, A; Cioffi, CL; Moss, N; Vankayalapati, H; Li, D Arf6 inhibitors and methods of synthesis and use thereof US Patent  US10849901 Publication Date 12/1/2020 
Target
Name:
ADP-ribosylation factor 6
Synonyms:
ARF6 | ARF6_HUMAN
Type:
Protein
Mol. Mass.:
20087.47
Organism:
Human
Description:
P62330
Residue:
175
Sequence:
MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS
  
Inhibitor
Name:
BDBM50027961
Synonyms:
CHEMBL3360257 | US10849901, Compound 126
Type:
Small organic molecule
Emp. Form.:
C20H21NO3S
Mol. Mass.:
355.451
SMILES:
CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(O)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: