Reaction Details Report a problem with these data
Target
TSC22 domain family protein 3
Ligand
BDBM18207
Substrate
n/a
Meas. Tech.
GILZ gene assays
IC50
2.10±n/a nM
Citation
 Garbaccio, RM; Kern, JC; Mulhearn, JJ; Brandish, PE Phosphonate linkers and their use to facilitate cellular retention of compounds US Patent  US10869929 Publication Date 12/22/2020 
Target
Name:
TSC22 domain family protein 3
Synonyms:
DSIP-immunoreactive peptide | DSIPI | Delta sleep-inducing peptide immunoreactor | GILZ | Glucocorticoid-induced leucine zipper protein | Protein DIP | T22D3_HUMAN | TSC-22-like protein | TSC-22-related protein | TSC-22R | TSC22D3 | hDIP
Type:
Protein
Mol. Mass.:
14799.51
Organism:
Human
Description:
Q99576
Residue:
134
Sequence:
MNTEMYQTPMEVAVYQLHNFSISFFSSLLGGDVVSVKLDNSASGASVVAIDNKIEQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLSPEEPAPESPQVPEAPGGSAV
  
Inhibitor
Name:
BDBM18207
Synonyms:
(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one | US10869929, Compound Dexamethasone | US11554172, Compound Dexamethasone | dexamethasone | dexamethasone (tetramethyl-rhodamine conjugated )
Type:
Steroid
Emp. Form.:
C22H29FO5
Mol. Mass.:
392.4611
SMILES:
[H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C |c:28,t:24|
Structure:
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