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Target
Alpha-synuclein
Ligand
BDBM481157
Substrate
n/a
Meas. Tech.
In Vitro Direct Determination By Fluorescence
Kd
0.490±0.2 nM
Citation
 Routier, S; Suzenet, F; Chalon, S; Buron, F; Vercouillie, J; Melki, R; Boiaryna, L; Guilloteau, D; Pieri, L Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases US Patent  US10906900 Publication Date 2/2/2021 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM481157
Synonyms:
US10906900, Reference 25a
Type:
Small organic molecule
Emp. Form.:
C21H17N3S
Mol. Mass.:
343.445
SMILES:
CN(C)c1ccc(cc1)C#Cc1cc2ccc(nc2[nH]1)-c1cccs1
Structure:
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