Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM482771
Substrate
n/a
Meas. Tech.
IPOne assay
EC50
435±n/a nM
Citation
 Eckhardt, M; Wagner, H; Peters, S Benzylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof US Patent  US10919859 Publication Date 2/16/2021 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM482771
Synonyms:
US10919859, Example 39
Type:
Small organic molecule
Emp. Form.:
C22H17F3N2O2
Mol. Mass.:
398.3778
SMILES:
OC(=O)[C@H]1C[C@@H]1c1ccc(NCc2cc(ccc2F)-c2c(F)cccc2F)cn1 |r|
Structure:
Search PDB for entries with ligand similarity: