Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM482782
Substrate
n/a
Meas. Tech.
IPOne assay
EC50
81.0±n/a nM
Citation
 Eckhardt, M; Wagner, H; Peters, S Benzylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof US Patent  US10919859 Publication Date 2/16/2021 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM482782
Synonyms:
US10919859, Example 50
Type:
Small organic molecule
Emp. Form.:
C25H25FN2O2
Mol. Mass.:
404.4766
SMILES:
CC(C)c1ccccc1-c1ccc(F)c(CNc2ccc(nc2)[C@H]2C[C@@H]2C(O)=O)c1 |r|
Structure:
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