Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50370571
Substrate
n/a
Meas. Tech.
TBD
Ki
57.0±n/a nM
Citation
 Martin, SF; Sahn, JJ; Linkens, KT Sigma receptor binders US Patent  US10954217 Publication Date 3/23/2021 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Homo sapiens (Human)
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM50370571
Synonyms:
CHEMBL4160064 | US10954217, Example 00236
Type:
Small organic molecule
Emp. Form.:
C23H23NO
Mol. Mass.:
329.4348
SMILES:
COc1cccc(c1)-c1ccc2CN(Cc3ccccc3)CCc2c1
Structure:
Search PDB for entries with ligand similarity: