Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM301729
Substrate
n/a
Meas. Tech.
Pharmacological Assay
EC50
12.0±n/a nM
Citation
 Eckhardt, M; Frattini, S; Langkopf, E; Wagner, H Indanyloxydihydrobenzofuranylacetic acids US Patent  US9597310 Publication Date 3/21/2017 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM301729
Synonyms:
US9597310, 19 | {(S)-6-[(R)-4-(4-Ethylcarbamoyl-phenoxy)-7-fluoro-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester
Type:
Small organic molecule
Emp. Form.:
C29H28FNO6
Mol. Mass.:
505.5341
SMILES:
CCNC(=O)c1ccc(Oc2ccc(F)c3[C@@H](CCc23)Oc2ccc3[C@H](CC(=O)OC)COc3c2)cc1 |r|
Structure:
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