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Target
Galectin-3
Ligand
BDBM494618
Substrate
n/a
Meas. Tech.
Fluorescence Anisotropy Assay
Kd
970±n/a nM
Citation
 Zetterberg, F; Leffler, H; Nilsson, U Alpha-D-galactoside inhibitors of galectins US Patent  US10988502 Publication Date 4/27/2021 
Target
Name:
Galectin-3
Synonyms:
LEG3_HUMAN | LGALS3 | MAC2
Type:
Enzyme
Mol. Mass.:
26156.54
Organism:
Homo sapiens (Human)
Description:
P17931
Residue:
250
Sequence:
MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
  
Inhibitor
Name:
BDBM494618
Synonyms:
3,4-Dichlorophenyl 3-deoxy-3-[4-(5-fluoro-2-thiophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-α-D-galactopyranoside | US10988502, Example 9
Type:
Small organic molecule
Emp. Form.:
C18H16Cl2FN3O4S2
Mol. Mass.:
492.372
SMILES:
OCC1O[C@H](Sc2ccc(Cl)c(Cl)c2)C(O)[C@H]([C@H]1O)n1cc(nn1)-c1ccc(F)s1 |r|
Structure:
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