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Target
Galectin-1
Ligand
BDBM494854
Substrate
n/a
Meas. Tech.
Fluorescence Anisotropy Assay
Kd
200±n/a nM
Citation
 Zetterberg, F; Leffler, H; Nilsson, U Alpha-D-galactoside inhibitors of galectins US Patent  US10988502 Publication Date 4/27/2021 
Target
Name:
Galectin-1
Synonyms:
14 kDa lectin | Galaptin | HPL | LEG1_HUMAN | LGALS1 | Lactose-binding lectin 1 | Lectin galactoside-binding soluble 1 | Putative MAPK-activating protein PM12
Type:
beta galactoside-binding protein
Mol. Mass.:
14713.53
Organism:
Homo sapiens (Human)
Description:
P09382
Residue:
135
Sequence:
MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD
  
Inhibitor
Name:
BDBM494854
Synonyms:
5-Bromo-2-cyano-pyridine-3-yl 3-deoxy-3-[4-(2-thiazolyl)-1H-1,2,3-triazol-1-yl]-1-thio-α-D-galactopyranoside | US10988502, Example 22
Type:
Small organic molecule
Emp. Form.:
C17H15BrN6O4S2
Mol. Mass.:
511.373
SMILES:
OCC1O[C@H](Sc2cc(Br)cnc2[N+]#[C-])C(O)[C@H]([C@H]1O)n1cc(nn1)-c1nccs1 |r|
Structure:
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