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Target
Somatostatin receptor type 1
Ligand
BDBM506539
Substrate
n/a
Meas. Tech.
SSTR1 I-125 Somatostatin Competition Binding Assay for Selectivity Versus SSTR4
IC50
6310±n/a nM
Citation
 Cheruvallath, Z; Green, J; Johnson, B; Schleicher, K; Sun, H; Tang, M Piperidinyl-3-(aryloxy)propanamides and propanoates US Patent  US11045457 Publication Date 6/29/2021 
Target
Name:
Somatostatin receptor type 1
Synonyms:
SOMATOSTATIN SST1 | SRIF-2 | SS-1-R | SS1-R | SS1R | SSR1_HUMAN | SSTR1 | Somatostatin receptor type 1 (SSTR1)
Type:
Enzyme
Mol. Mass.:
42692.81
Organism:
Homo sapiens (Human)
Description:
P30872
Residue:
391
Sequence:
MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCTSRITTL
  
Inhibitor
Name:
BDBM506539
Synonyms:
US11045457, Example 139 | US11045457, Example 177
Type:
Small organic molecule
Emp. Form.:
C18H26F3N3O2
Mol. Mass.:
373.4131
SMILES:
C[C@@H]1C[C@H](CCN1C)NC(=O)C(C)(C)COc1ncccc1C(F)(F)F |r|
Structure:
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