| Assay Method Information | |
| | Inhibition of CYP Enzyme Activity In Vitro |
| Description: | The ability of the tested compounds to inhibit a panel of CYP enzymes in vitro was assessed using a series of human liver microsome assays. Half-maximal inhibitory concentration (IC50) was calculated for compounds demonstrating mean inhibition greater than 50% compared to a reference inhibitor. |
| Affinity data for this assay | |
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