| Assay Method Information | |
| | Biochemical Evaluation |
| Description: | The BTK/BTK (C481S) inhibitory activity of compound of formula A was determined in Reaction Biology Corporation, One Great Valley Parkway, Malvern, PA, USA. Full-length human BTK/BTK (C481S) enzyme and 20 μM peptide substrate [KVEKIGEGTYGVVYK] were used. The concentration of tested ATP was 10 μM. Starsporin was used as standard, of which IC50 was 3.94 nM. |
| Affinity data for this assay | |
|---|---|
| If you find an error in this entry please send us an E-mail | |