Assay Method Information | |
| ChEMBL_1859087 (CHEMBL4359943) |
Description: | Inhibition of IRAK4 in human THP1-Xblue-MD2-CD14 cells assessed as reduction in LPS-induced NFkappaB transcription by measuring alkaline phosphatase level preincubated for 1 hr followed by LPS stimulation and measured after 20 hrs by quanti-blue reagent based reporter assay |
Affinity data for this assay | |
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