| Assay Method Information | |
| | ChEMBL_2486692 |
| Description: | Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing halide-sensitive yellow fluorescent protein assessed as increase in iodide influx preincubated with compound for 24 hrs followed by compound washout and measured after 30 mins of stimulation with forskolin/genistein by fluorescence microplate reader |
| Affinity data for this assay | |
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