| Assay Method Information | |
| | Fluorescence Polarization (FP) Assay |
| Description: | The labeled fragment can be distinguished from full-length MKK by a change in fluorescence polarization. MKK6 was used as a substrate because it could produce large quantities of the full-length protein, sufficient for HTS. MKK6 inhibitors do not bind in the active site but in a separate exosite. |
| Affinity data for this assay | |
|---|---|
| If you find an error in this entry please send us an E-mail | |