| Assay Method Information | |
| | ChEMBL_2014897 (CHEMBL4668475) |
| Description: | Allosteric inhibition of [H2N-LN(pY)AQLWHA(PEG8)LTI(pY)ATIRRF-amide]-activated N-terminal His6-fused human full length SHP2 (Met 1 to Arg 593 residues) expressed in Escherichia coli BL21 (DE3) cells using DiFMUP as substrate preincubated for 30 followed by substrate addition and by fluorescence method |
| Affinity data for this assay | |
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