| Assay Method Information | |
| | ChEMBL_2163192 (CHEMBL5048053) |
| Description: | Inhibition of MTA-bound human PRMT5 co-complexed with MEP50 using biotin labelled histone H4 peptide (1 to 15) as substrate assessed as inhibition of tritiated methyl group transfer from SAM to histone H4 preincubated for 20 mins followed by SAM addition and measured after 20 mins by scintillation counting analysis |
| Affinity data for this assay | |
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