| Assay Method Information | |
| | ChEMBL_2666783 |
| Description: | Binding affinity to recombinant human His10-tagged SOS1 (564 to 1049 residues) assessed as inhibition of GST-tagged human KRAS G12C mutant (1 to 169 residues) interaction with SOS1 preincubated for 15 mins followed by KRAS addition and measured after 2 hrs by FRET assay |
| Affinity data for this assay | |
|---|---|
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