Assay Method Information | |
| ChEMBL_1995536 (CHEMBL4629431) |
Description: | Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human H460-MX20 cells assessed as effect on topotecan-induced cytotoxicity by measuring topotecan IC50 at 0.5 uM after 72 hrs by MTT assay (Rvb = 1319.20 +/- 356.14 nM) |
Affinity data for this assay | |
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