| Assay Method Information | |
| | RSK1-4 Kinase Assay |
| Description: | Table 24: Selected compounds of the invention were tested for their inhibitory potential of RSK1, RSK2, RSK3 and RSK4 kinases via the Eurofins KinaseProfiler™ service, using a 9-point concentration response curve up to a top concentration of 10 μM. The radiometric kinase activity assays were run at approximately the ATP Km for each kinase |
| Affinity data for this assay | |
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