| Assay Method Information | |
| | ChEMBL_2462477 |
| Description: | Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as potentiation of acetylcholine induced channel current amplitude by measuring acetylcholine EC50 at 10 uM preincubated for 2 mins followed by co-application with acetylcholine for 20 sec by two-electrode voltage clamp recording method (Rvb = 270.14 +/- 75.06 uM) |
| Affinity data for this assay | |
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